Isoleucine

Description

What is Isoleucine?

Isoleucine, an amino acid that makes up between 2% and 10% of most proteins, is a common one. Isoleucine amino acid, one of several so-called essential amino acids for humans, rats, and other higher animals, was first isolated from fibrin, a blood clot-forming protein, in 1904.i.e., they need food sources because they can’t make it. Isoleucine amino acid is made in plants and microorganisms from the amino acid threonine.

Basic information

Product Name:	L-Isoleucine
Synonyms:	Isoleucine; (S)-Isoleucine; L-(+)-Isoleucine; Isoleucinum; Isoleucina;
CAS:	73-32-5
MF:	C6H13NO2
MW:	131.17
EINECS:	200-798-2
Product Categories:	Biochemistry;Nutritional Supplements;L-Amino Acids;Amino Acids; APIs; Biochemical Engineering

Chemical Structure

L-Isoleucine

Chemical Properties

Melting point	288 °C (dec.) (lit.)
alpha	41 º (c=4, 6N HCl)
Boiling point	225.8±23.0 °C(Predicted)
density	1.2930 (estimate)
FEMA	4675 \| L-ISOLEUCINE
refractive index	40.5 ° (C=4, 6mol/L HCl)
Fp	168-170°C
storage temp.	Store below +30°C.
solubility	1 M HCl: 50 mg/mL
pka	2.32, 9.76(at 25℃)
form	powder
color	White to Off-white
PH	5.5-6.5 (40g/l, H2O, 20℃)
optical activity	[α]20/D +41.0±1°, c = 5% in 6 M HCl
Water Solubility	41.2 g/L (50 ºC)
λmax	λ: 260 nm Amax: 0.07 λ: 280 nm Amax: 0.05
Sublimation	168-170 ºC
Merck	14,5179
JECFA Number	2118
BRN	1721792
InChIKey	AGPKZVBTJJNPAG-WHFBIAKZSA-N

Isoleucine Usage And Synthesis

L-Isoleucine Uses

The immune system, including cells, immune organs, and reactive substances, can be enhanced by isoleucine.Host defense peptides known as -defensins, which have the ability to regulate both innate and adaptive immunity, have also been shown to be induced by isoleucine, according to recent research.

By increasing the expression of -defensins, isoleucine amino acid administration can also reverse the effects of some pathogens on human and animal health. As a result, the purpose of this review is to summarize the connection between immune functions and branched chain amino acids while also emphasizing the impact of isoleucine on immunity.

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