Ca-AKG vs AKG: Bulk Supplements Ingredients

What is Ca-AKG?

Calcium Alpha-Ketoglutarate (Ca-AKG) is a compound that combines calcium with alpha-ketoglutarate (AKG), a molecule involved in the Krebs cycle, which is critical for energy production in cells. Ca-AKG is commonly used in sports nutrition and anti-aging supplements.

What is AKG?

AKG is a compound created naturally in our body but diminishes with age. It promotes longer health and prevents inflammation. It modulates the pathways responsible for healthy ageing including DNA demethylation.

Ca-AKG vs AKG

Amino Acids Calcium alpha-ketoglutarate (Ca-AKG) is a form of alpha-ketoglutarate (AKG) that’s more bioavailable and may have more benefits than plain AKG. AKG powder manufacturer, Essence Medchem Co., Ltd produces Alpha-Ketoglutarate with a purity of up to 98%, and stocked in the U.S. We have own factory and can provide customized services according to your requirements, as well as customized services such as OEM.

AKG powder

Ca-AKG vs AKG: Manufacturing Process, Uses, Supplement Formulations, Dosage, Safety, and Supplement Combinations

1. Alpha-Ketoglutarate (AKG) Manufacturing

Chemical Synthesis:

  • Starts with the oxidation of glutamic acid.
  • Uses catalysts such as ammonium sulfate.
  • Purified through crystallization and drying.

Alpha-Ketoglutarate (AKG) Powder Supplier COA

Specification Alpha-Ketoglutarate (AKG) Powder
Chemical Formula C5H6O5
Molecular Weight ~146.11 g/mol
Appearance White crystalline powder
Solubility Water-soluble
pH (1% solution) 2.5 – 4.0
Stability Less stable, prone to oxidation
Bioavailability Rapid absorption
Calcium Content None
Taste Sour, slightly acidic
Purity ≥98%
Heavy Metals (As, Pb, Hg, Cd) <10 ppm
Loss on Drying <3.0%
Mesh Size 80-100 mesh
Shelf Life 2-3 years
Storage Conditions Cool, dry place, sealed container
Main Uses Energy production, muscle recovery, ammonia detoxification
Common Dosage 1,000–6,000 mg/day
Side Effects Possible mild nausea, no calcium-related risks

2. Calcium Alpha-Ketoglutarate (Ca-AKG) Manufacturing

Produced by binding calcium to AKG via a neutralization reaction:

  • AKG is reacted with calcium salts (e.g., calcium carbonate or calcium hydroxide).
  • Ensures stable calcium chelation for better absorption.
  • Dried, milled, and converted into a supplement-grade powder.

Ca-AKG Powder Factory COA

Specification Ca-AKG (Calcium Alpha-Ketoglutarate) Powder
Chemical Formula C5H6CaO5
Molecular Weight ~184.16 g/mol (without calcium)
Appearance White to off-white powder
Solubility Water-soluble
pH (1% solution) 6.5 – 8.0
Stability More stable due to calcium chelation
Bioavailability Sustained release, moderate absorption
Calcium Content ~15-20% Calcium
Taste Slightly bitter to neutral
Purity ≥98%
Heavy Metals (As, Pb, Hg, Cd) <10 ppm
Loss on Drying <5.0%
Mesh Size 80-100 mesh
Shelf Life 2-3 years
Storage Conditions Cool, dry place, away from light
Main Uses Longevity, bone health, metabolism support
Common Dosage 600–1,200 mg/day
Side Effects Possible mild GI discomfort, excessive calcium risk

3. Purity & Testing Requirements

Ensure bulk orders meet the following quality standards:

  • Purity: ≥98% (HPLC Tested)
  • Heavy Metals: <10 ppm (Lead, Mercury, Arsenic, Cadmium)
  • Microbial Limits: <1,000 CFU/g (Bacterial), <100 CFU/g (Yeast & Mold)
  • Solubility Testing: Water-soluble, neutral pH (Ca-AKG is more stable)
  • Third-Party Lab Testing: Required for USA & EU compliance

How Does Ca-AKG Compare to AKG

1. Calcium Alpha-Ketoglutarate (Ca-AKG)

  • Enhanced Stability & Bioavailability: The calcium component aids in prolonged release.
  • Bone Health: Calcium supports bone density and strength.
  • Longevity Research: Studies indicate Ca-AKG extends lifespan in animal models.

2. Alpha-Ketoglutarate (AKG)

Supplement Formulations of Ca-AKG vs AKG

1. Powder

  • AKG: Typically used in pre-workouts or metabolic support blends.
  • Ca-AKG: Often found in anti-aging formulations.

2. Capsules/Tablets

  • Used for convenience and precise dosing.

3. Liquid

  • AKG formulations for faster absorption.

4. Multi-ingredient Blends

  • Combined with creatine, BCAAs, or nitric oxide boosters.

As a bulk ingredient suppliers in the nutritional supplement industry, Ca-akg powder is available for wholesale distribution. Our product meets the highest standards of purity, safety, and efficacy, making it an ideal choice for supplement manufacturers, research institutions, and pharmaceutical companies.

Bulk Supplements Ingredients

Popular Supplement Combinations With Ca-AKG vs AKG

1. For Longevity & Anti-Aging

2. For Athletic Performance & Recovery

  • AKG + Creatine + Citrulline Malate + Beta-Alanine

3. For Bone Health

  • Ca-AKG + Vitamin D3 + Magnesium + K2

Dosage

Alpha-Ketoglutarate (AKG) Powder

  • General Health & Anti-Aging: 1,000–3,000 mg/day.
  • Athletic Performance: 3,000–6,000 mg/day.

Ca-AKG (Calcium Alpha-Ketoglutarate) Powder

  • Anti-Aging & Longevity: 600–1,200 mg/day.
  • Bone Health: 800–1,500 mg/day.

Safety

YES. Calcium alpha-ketoglutarate (Ca-AKG) is generally considered safe, and is generally recognized as safe (GRAS). However, some side effects have been reported, and more research is needed to understand its long-term safety.

Contact Us for Wholesale Orders

Are you interested in wholesale Ca-AKG powder? Contact our sales team today to discuss wholesale pricing, MOQ, and custom packaging shipping.

We look forward to serving you!

Region Shipping Time (Air Freight) Shipping Time (Sea Freight)
USA (Domestic) 3-7 days 25-40 days
Europe (Germany, France, UK, Netherlands) 5-10 days 25-40 days
China/India to USA 7-14 days 30-50 days
China/India to Europe 10-15 days 35-55 days

*Tip: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Customer Feedback Report

-Sports ***vity Mar***

AKG Powder Feedback

“We’ve used AKG in our pre-workout formulations. It dissolves well and provides excellent energy and endurance support.” – (Sports Supplement Manufacturer, California)

“The purity and consistency of the AKG powder are great. We noticed increased demand from bodybuilders and endurance athletes.” – (Private Label Brand, New York)

Ca-AKG Powder Feedback

“The stability and sustained release of Ca-AKG make it a game-changer for our longevity and anti-aging formulations.” – (Longevity Supplement Brand, Florida)

“Our customers prefer Ca-AKG over standard AKG for its calcium benefits. Great for metabolic and bone health support.” – (Health Supplement Supplier, Texas)

-*** Supplement In***

AKG Powder Feedback

“A well-accepted raw material for performance enhancement. Tested for purity, meets our high European standards.” – (Sports Nutrition Manufacturer, Berlin)

“Excellent mixability in liquid supplements. Works well in BCAA and NO-boosting formulations.” – (Supplement Formulator, Hamburg)

Ca-AKG Powder Feedback

“Great stability in our capsule formulations. Customers like the additional calcium benefits.” – (Longevity Product Manufacturer, Munich)

“Clinically backed longevity benefits are increasing market interest.” – (Anti-Aging Brand, Frankfurt)

Ca-AKG vs AKG-Market Trends & Feedback Overview

Aspect AKG Powder Ca-AKG Powder
Market Demand High in sports nutrition, nootropics Growing in longevity, wellness
Main Uses Energy, nitric oxide, endurance Anti-aging, bone health, metabolism
Bioavailability Fast absorption Sustained release, stable
Mixability Good, but slightly acidic taste Neutral taste, easy to mix
Customer Preference Athletes, fitness enthusiasts Biohackers, aging population
Cost More affordable Premium-priced
Growth Potential Stable, well-established Increasing in longevity sector

Would you like a customized wholesale pricing comparison or bulk sourcing details for these ingredients?

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