Alpha-Ketoglutarate (AKG) is a beneficial ingredient in nutritional supplements, valued for its role in energy metabolism, muscle performance, anti-aging, and overall health. When used correctly, it can significantly enhance physical performance and metabolic function, making it a key component in various health and fitness formulations.
What is Alpha-ketoglutarate (AKG)
Alpha-Ketoglutarate (AKG) is a critical intermediate in the Krebs cycle, which is essential for energy production in cells. It plays a role in amino acid metabolism, supports cellular energy production, and contributes to overall health and longevity.
Manufacturing Process of Alpha-Ketoglutarate (AKG)
- The production of Alpha-ketoglutarate (AKG) amino acid for supplementation involves several steps:
- Fermentation Process: Maxmedchem derive Alpha-ketoglutarate (AKG) from microbial fermentation, particularly from bacteria such as Corynebacterium glutamicum.
- Chemical Synthesis: Another method involves the oxidation of glutamic acid, which leads to the formation of AKG.
- Purification: The resulting Alpha-ketoglutarate (AKG) is then purified through crystallization and filtration methods.
- Formulation: Dietary supplement manufacturers process Alpha-ketoglutarate (AKG) into different supplement forms such as capsules, powders, and liquid solutions..
Wholesale Alpha-Ketoglutarate (AKG) Powder – Bulk MOQ
Appearance | White powder |
Solubility | Soluble in water |
Purity | ≥ 99% (HPLC) |
pH (5% Solution) | 2.0 – 3.5 |
Loss on Drying | ≤ 2.0% |
Heavy Metals | ≤ 10 ppm |
Lead (Pb) | ≤ 3 ppm |
Arsenic (As) | ≤ 1 ppm |
Cadmium (Cd) | ≤ 1 ppm |
Mercury (Hg) | ≤ 0.1 ppm |
Total Plate Count | ≤ 1,000 CFU/g |
Yeast & Mold | ≤ 100 CFU/g |
E. coli | Negative |
Salmonella | Negative |
Storage Conditions | Store in a cool, dry place away from light and moisture |
Shelf Life | 2 years |
Alpha-Ketoglutarate Powder Manufacturer, Essence Medchem Co., Ltd produces AKG powder with a purity of 99%, and stocked in the U.S. We have own factory and can provide customized services according to your requirements, as well as customized services such as OEM.
Uses of Alpha-Ketoglutarate in Nutritional Supplements
- Muscle Growth: Alpha-ketoglutarate seems to help the body rebuild muscle and reduce muscle loss after surgery or trauma. It might also have anti-aging effects.
- Anti-Aging Properties: Research suggests that Alpha-Ketoglutarate (AKG) supplementation may extend lifespan and improve cellular energy production by supporting mitochondrial
- Bone Health: Alpha-Ketoglutarate (AKG) plays a role in collagen synthesis, which is crucial for maintaining strong bones and joints.
- Metabolic Support: It aids in ammonia detoxification, which is important for maintaining nitrogen balance in the body.
- Exercise Performance: Enhances endurance by reducing exercise-induced fatigue and promoting ATP production.
Supplement Formulations of Alpha-Ketoglutarate
AKG is formulated in various supplement forms, including:
- Alpha-Ketoglutarate (AKG) Powder: Pure alpha-ketoglutarate powder for flexible dosing.
- Alpha-Ketoglutarate (AKG) Capsules/Tablets: Convenient for standardized dosing and controlled release.
- Alpha-Ketoglutarate (AKG) with Other Amino Acids: Often combined with L-arginine (AAKG) to support nitric oxide production and vascular health.
- Pre-Workout & Performance Blends: Included in performance-enhancing supplements for increased energy and endurance.
As a bulk ingredient supplier in the nutritional supplement industry, Alpha-Ketoglutarate (AKG) Powder is available for wholesale distribution. Our product meets the highest standards of purity, safety, and efficacy, making it an ideal choice for supplement manufacturers, research institutions, and pharmaceutical companies.
Best Supplement Combinations With Alpha-Ketoglutarate (AKG)
Raw supplement ingredients suppliers Alpha-Ketoglutarate (AKG) is commonly paired with other compounds to maximize its effects:
L-Arginine (AAKG): Enhances nitric oxide production for improved circulation and endurance.
Creatine: Supports ATP production and muscle performance.
BCAA (Branched-Chain Amino Acids): Aids in muscle recovery and reduces fatigue.
Glutamine: Supports immune function and intestinal health.
Vitamin C & E: Acts as antioxidants to protect against oxidative stress.
Recommended Dosage of Alpha-Ketoglutarate
- General Health: 300–1000 mg per day
- Muscle Growth & Performance: 1.5–3 grams per day, typically before workouts
- Anti-Aging & Longevity: 2–4 grams per day, as studied in age-related research
Safety & Potential Side Effects
Alpha-Ketoglutarate (AKG) is generally considered safe when taken in recommended doses. However, potential side effects may include:
- Mild gastrointestinal discomfort (bloating, nausea)
- Possible interactions with medications that affect nitric oxide pathways
- Overuse may lead to imbalances in amino acid metabolism
Contact Us for Wholesale Orders
Are you interested in wholesale AKG powder? Contact our sales team today to discuss bulk pricing, MOQ, and custom packaging options. We look forward to serving you!
*Tip: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Customer Feedback:
Here’s what customers from different countries are saying about our AKG powder:
USA – We’ve been sourcing AKG from Essence medchem Co., Ltd supplier for over a year, and the consistency in purity and quality is unmatched. Our customers love it!” – John D., Nutritional Brand Owner.
Germany – Excellent solubility and no impurities. Works great in our performance blends!” – Anna M., Sports Nutrition Manufacturer.
France – Fast shipping and premium quality. Our anti-aging product line has seen great results!” – Pierre L., Health Supplement Developer.
Netherlands – We appreciate the thorough COA provided with every batch. Reliable supplier!” – Erik V., Research Scientist.
UK – Great customer service and competitive pricing. Our athletes have reported noticeable endurance benefits.” – Mark S., Sports Supplement Brand.
Canada – The best AKG powder we’ve tested so far. High purity and excellent customer support.” – Sarah B., Health & Wellness Company.
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