ZANAMIVIR HYDRATE
- Chemical Name:ZANAMIVIR HYDRATE
- CAS No.:139110-80-8
- MF: C12H20N4O7
- MW:332.31
- Specification: USP|EP|BP
- Purity:>98% or As customer requested
- Color: white to beige
- Solubility:H2O: soluble10mg/mL, clear
- Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;APIs
- Test method: HPLC
Description
ZANAMIVIR HYDRATE is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles. It was launched as Relenza in Australia for treatment of human influenza A and B virus infections.
Human studies have shown that ZANAMIVIR HYDRATE is effectivewhen administered before or after exposure to the influenzavirus. If administered before exposure to the virus, the drugreduced viral propagation, infectivity, and disease symptoms.If administered after exposure, the drug reduces propagation,viral titer, and illness.
Zanamivir Hydrate 98 Basic information
Product Name: | ZANAMIVIR HYDRATE |
Synonyms: | ZANAMIVIR; 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid; |
CAS: | 139110-80-8 |
MF: | C12H20N4O7 |
MW: | 332.31 |
EINECS: | 691-117-1 |
Product Categories: | Inhibitors; Anti-virals; Anti-viral Compounds; Intermediates & Fine Chemicals; Pharmaceuticals |
Zanamivir Hydrate 98 Chemical Structure
Zanamivir Hydrate Chemical Properties
Melting point | 2560C (dec.) |
alpha | D20 +40.9° (c = 0.9 in water) |
density | 1.75±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | H2O: soluble10mg/mL, clear |
form | powder |
pka | 3.82±0.70(Predicted) |
color | white to beige |
optical activity | [α]/D +30 to +40°, c = 1 in H2O |
InChIKey | ARAIBEBZBOPLMB-UFGQHTETSA-N |
Zanamivir Hydrate Usage And Synthesis
Chemical Properties | Colorless Crystalline Solid |
Uses | Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral |
antineoplastic, anti-metabolite | |
Therapeutic Function | Antiviral |
Pharmaceutical Applications | A synthetic neuraminidase inhibitor formulated for administration by inhalation. |
MSDS: MSDS available.
COA: COA can be available if you send us inquiry.
Email us at: info@maxmedchem.com for more details.