Urolithin A has emerged as a promising biosynthesis particularly in promoting cellular health and longevity. While it can be derived from natural sources, one of the most innovative and efficient methods of production is through bacterial fermentation. This blog will explore the bacterial fermentation production process of Urolithin A, along with quality control measures, raw material traceability, and its functional applications.
Urolithin A Fermentation Process
Essence medchem Co., Ltd Manufacturing Bacterial fermentation process involves using specific strains of bacteria to convert precursor compounds into Urolithin A. This biotechnological approach offers a sustainable and scalable method for production.
1. Inoculation
Selected bacterial strains are inoculated into the culture medium. Conditions such as temperature, pH, and anaerobic environment are optimized for bacterial growth and metabolism.
2. Fermentation
The fermentation process typically lasts from several hours to a few days, during which the bacteria metabolize the ellagitannins into Urolithin A. Continuous monitoring of pH and temperature ensures optimal growth conditions.
3. Harvesting
Once fermentation is complete, the biomass is separated from the culture medium through centrifugation or filtration.
4. Extraction and Purification:
Urolithin A is extracted from the supernatant using solvent extraction techniques. Further purification may involve chromatography to isolate Urolithin A in a highly pure form.
Urolithin A Quality Control
Microbial Testing: Samples are tested for pathogenic bacteria and fungi to ensure safety.
Heavy Metals and Residual Solvents: Testing for contaminants like heavy metals and any remaining solvents from the extraction process is performed.
Urolithin A Powder Suppliers COA
Parameter | Specification |
---|---|
Appearance | Fine powder |
Color | Off-white to light yellow |
Odor | Characteristic |
Assay (HPLC) | ≥ 98.0% |
Loss on Drying | ≤ 5.0% |
Residue on Ignition | ≤ 2.0% |
Heavy Metals | ≤ 10 ppm |
Arsenic (As) | ≤ 1 ppm |
Lead (Pb) | ≤ 2 ppm |
Cadmium (Cd) | ≤ 1 ppm |
Mercury (Hg) | ≤ 0.1 ppm |
Total Plate Count | ≤ 1,000 cfu/g |
Yeast & Mold | ≤ 100 cfu/g |
E. coli | Negative |
Salmonella | Negative in 25g |
Staphylococcus aureus | Negative |
Pesticides | Complies with relevant regulations |
Solvent Residue | Complies with relevant regulations |
GMO Status | Non-GMO |
Allergens | Free from allergens (gluten, soy, dairy, etc.) |
Shelf Life | 24 months in sealed containers stored in cool, dry place |
Functional of Urolithin A Powder
Urolithin A powder offers a range of functional applications, particularly in health and wellness.
Anti-Aging and Cellular Health
- Urolithin A is known to promote autophagy, a vital cellular process that helps remove damaged cells, thus supporting overall cellular health and longevity.
Muscle Health
- Studies suggest that Urolithin A can enhance mitochondrial function, leading to improved muscle endurance and recovery. This makes it a valuable supplement for athletes and active individuals.
Neuroprotective Effects
- Emerging research indicates that Urolithin A may provide neuroprotective benefits, potentially aiding in the prevention of neurodegenerative diseases.
Gut Health
- As a metabolite produced by gut microbiota, Urolithin A can contribute to a balanced microbiome and support digestive health.
Urolithin A Powder of Application
Urolithin A powder is used in various fields due to its potential health benefits. Here are some key areas:
- Raw Supplement Ingredients Supplements:
- Bulk ingredient suppliers urolithin A powder is commonly included in supplements aimed at promoting cellular health, longevity, and overall wellness.
- Functional Foods:
- It can be added to health foods and beverages designed to support gut health and metabolic function.
- Sports Nutrition:
- Urolithin A is recognized for its potential to enhance muscle recovery and endurance, making it popular in products aimed at athletes and fitness enthusiasts.
- Anti-Aging Products:
- Due to its role in promoting autophagy and cellular regeneration, Urolithin A is often incorporated into anti-aging formulations.
- Cosmetics and Skin Care:
- Some cosmetic products leverage its antioxidant properties to promote skin health and reduce signs of aging.
- Pharmaceuticals:
- Research into Urolithin A neuroprotective effects may lead to its incorporation into pharmaceutical formulations targeting neurodegenerative diseases.
What Ingredients Can Urolithin A Be Formulated With
Urolithin A can be effectively formulated with a variety of complementary ingredients to enhance its benefits and create synergistic effects. Here are some key ingredients that are often combined with Urolithin A:
- Ellagitannins:
- Found in pomegranates and berries, these compounds can work synergistically with Urolithin A, as they are precursors that contribute to its production in the gut.
- Probiotics:
- Strains like Lactobacillus and Bifidobacterium can support gut health and enhance the metabolism of ellagitannins, potentially increasing Urolithin A production.
- Omega-3 Fatty Acids:
- Ingredients like fish oil or flaxseed oil can complement Urolithin A anti-inflammatory properties.
- Vitamins C and E:
- Vitamins C and E, selenium, and other antioxidant-rich compounds can enhance the overall antioxidant profile of the formulation.
- Curcumin:
- This compound from turmeric may provide additional anti-inflammatory and antioxidant benefits when combined with Urolithin A.
- Coenzyme Q10 (CoQ10):
- Known for its role in mitochondrial function, CoQ10 can enhance the cellular energy-boosting effects of Urolithin A.
- Resveratrol:
- This polyphenol, found in grapes and berries, may have similar cellular health benefits and can complement the effects of Urolithin A.
- Fiber:
- Ingredients like inulin or psyllium can promote gut health, supporting the microbiome’s ability to produce Urolithin A.
- Adaptogens:
- Herbs like ashwagandha or rhodiola may enhance overall resilience and stress response, supporting the benefits of Urolithin A.
Conclusion
As leaders in the urolithin a powder manufacturing industry, Our R&D team continuously explores new applications, ensuring that our clients have access to cutting-edge ingredients.Wholesale urolithin a powder health ingredients and API ingredients Contact Us.