Vancomycin Hydrochloride

Description

Vancomycin hydrochloride is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain bacterial infections, such as infections caused by Clostridium difficile and Staphylococcus aureus.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Vancomycin Hydrochloride for Injection and other antibacterial drugs, Vancomycin Hydrochloride for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.

Vancomycin hydrochloride Basic information

Product Name:	Vancomycin hydrochloride
Synonyms:	vancocinehydrochloride; LYPHOCIN; Vancomycin Hydrochloride (4 vials, each vial contains 99,300 mcg of vancomycin activity);Vancomycin Hydrochloride (4 vials, each vial contains 100,500 mcg of vancomycin activity);VANCOMYCIN, HYDROCHLORIDE, STREPTOMYCES ORIENTALIS;VANCOR;VANCOCIN;VANCOCIN HYDROCHLORIDE
CAS:	1404-93-9
MF:	C66H76Cl3N9O24
MW:	1485.71
EINECS:	604-193-8
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Antibiotics and Antimycotics;
Mol File:	1404-93-9.mol

Vancomycin hcl Chemical Structure

Vancomycin hydrochloride

Vancomycin hcl Chemical Properties

Melting point	>190°C (dec.)
alpha	[α]D20 -30～-40゜ (c=1, H2O)
Fp	87℃
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL, clear, yellow
form	Powder
color	colorless to faint yellow or tan
PH	pH (50g/l, 25℃) : 2.5～4.5
Water Solubility	Soluble in water. Slightly soluble in methanol, ethanol and dimethylsulfoxide.
Sensitive	Hygroscopic
Merck	13,9995
BRN	3704657

Aerovanc Usage And Synthesis

Uses	It has a narrow antimicrobial spectrum which is mainly against Gram-positive bacteria. It is a kind of narrow-spectrum antibiotics only effective in treating gram-positive bacteria, such as Streptococcus pneumoniae, Neisseria gonorrhoeae and enterococci; etc which are all sensitive to this drug. Staphylococcus aureus is particularly sensitive to this product. Its mechanism of action is inhibition of bacterial cell wall synthesis; it mainly binds to the bacterial cell wall and leaving some kinds of amino acids being unable to enter into the glycopeptides of the cell wall.
Chemical Properties	off white powder
Uses	Amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Inhibits bacterial cell wall synthesis by binding to peptidoglycan. Antibacterial.
Uses	Vancomycin hydrochloride is the salt of a glycopeptide antibiotic isolated from Amycolatopsis orientalis in 1956. Vancomycin exhibits potent activity against Gram positive bacteria and is highly effective against MRSA in vitro and in vivo. Vancomycin interferes with cell wall synthesis by binding to D-alanine-D-alanine residues.