Urolithin A vs Fisetin

As a cosmetics manufacturer, we deeply understand that Urolithin A and Fisetin reflects growing interest and innovation in the wellness market, particularly as consumers become more focused on anti-aging, skin health, and holistic well-being. And then what is Urolithin A and Fisetin, this article will give you a detailed introduction.

What is Urolithin A Sources?

Pomegranates and walnuts are rich in ellagic acid and urolithin A can be synthesized starting with ellagic acid or its derivatives, undergoing hydrolysis (to remove ester groups) and then reductive cyclization (to form the cyclic structure), followed by purification to ensure a pure product.

What is Fisetin Sources?

In the laboratory, fisetin can be synthesized by starting with kaempferol or quercetin, and using specific chemical modifications like hydroxylation to introduce the functional groups required to form fisetin. The process may involve catalytic reagents or metal-based catalysts to optimize yields. Once synthesized, fisetin is purified through chromatography, ensuring a high-quality compound for use in dietary supplement products.

Can You Take Urolithin A vs Fisetin Together?

Yes, Taking both together could provide a well-rounded approach to overall health and anti-aging. Urolithin A is known for its ability to support mitochondrial health, helping with cellular energy production. It’s often used in dietary supplements for its potential to rejuvenate cells and promote longevity. Fisetin, on the other hand, is a powerful antioxidant with anti-inflammatory properties. It’s often used for its potential to improve brain health, support healthy aging, and help protect cells from oxidative stress.

While Urolithin A focuses on improving cellular function, Fisetin offers support by fighting oxidative stress and inflammation, which can contribute to various health concerns.

How High Quality Fisetin Can Transform the Anti-aging Market?

Fisetin supplements can come in different forms in anti-aging market, the most common being loose powders and capsules.

Capsules

You will enjoy taking our fisetin in liposomal capsules simply because of its convenience. Each capsule holds a pre-set dose of fisetin, so you don’t have to fuss with measurements. These are also much easier to take with you on the go.

Powder

We offer fisetin in powder form, meant to be dissolved in water. Fisetin powders offer more flexibility in dosing, as you can start out with lighter doses and work your way up to larger ones with the same product.

How to Incorporate Urolithin A into My Antioxidant Strategy?

Incorporating Urolithin A into your antioxidant strategy can enhance your approach to cellular health, mitochondrial function, and anti-aging by targeting both oxidative stress and mitochondrial dysfunction. Here’s how you can integrate Urolithin A into your antioxidant strategy for maximum benefit:

1.Combine Urolithin A with Other Antioxidants

Since UA targets mitochondrial health specifically, combining it with other antioxidants that combat oxidative stress throughout the body can create a more comprehensive antioxidant strategy. Some effective combinations include:

• Vitamin C and E: These are classic antioxidants that protect against oxidative damage from free radicals. Vitamin C neutralizes free radicals in the water-soluble parts of the cell, while Vitamin E acts in fat-soluble environments (like cell membranes).
• Coenzyme Q10 (CoQ10): Like Urolithin A, CoQ10 supports mitochondrial health and energy production. Together, they can enhance cellular energy while reducing oxidative damage.
• Curcumin: This active compound in turmeric has both anti-inflammatory and antioxidant properties, further reducing oxidative damage.
• Resveratrol: Known for its ability to activate sirtuins (proteins that promote cell survival and longevity), resveratrol can enhance the cellular protective effects of Urolithin A.

By combining Urolithin A with a variety of antioxidants, you can create a synergistic effect that addresses oxidative stress at both the cellular and mitochondrial levels.

2.Include Urolithin A in a Comprehensive Anti-Aging Routine

• Physical Activity: Regular exercise, especially resistance training, stimulates mitophagy naturally. Exercise, combined with Urolithin A supplementation, could enhance mitochondrial turnover and efficiency, which supports muscle health and overall vitality.
• Intermittent Fasting or Caloric Restriction: These practices can increase autophagy and mitophagy, complementing the action of Urolithin A and boosting its effects.
• Sleep Optimization: Adequate sleep is critical for mitochondrial repair and recovery. Ensuring quality sleep allows the body to maximize the repair benefits from Urolithin A and other antioxidants.

Together, these lifestyle strategies can help enhance Urolithin A impact on longevity, energy, and overall health.

3.Choose High-Quality Urolithin A Sources

Our Dachi platform will provide you with protection from the following high quality sources of urolixin A：

• High Purity Standards: Maxmedchem ensures that all of its products, including Urolithin A, undergo rigorous testing to meet the highest purity standards. Their Urolithin A is synthesized to be highly pure, making it suitable for research, clinical studies, and further formulation into supplements.
• State of the Art Manufacturing: Maxmedchem operates advanced manufacturing facilities equipped with cuttingedge technology.This allows them to produce Urolithin A in large quantities without compromising on quality.
• Transparent Sourcing: The company takes great care in sourcing raw materials from reputable suppliers, ensuring that only the best ingredients are used in production. They maintain a strong traceability system throughout the supply chain, which ensures consistent product quality.
• Certifications and Compliance: Maxmedchem adheres to Good Manufacturing Practices (FDA) and other relevant certifications, guaranteeing that their products meet industry standards for safety and efficacy. Their laboratories are also ISO-certified, providing further assurance to clients.
• Customized Solutions: Whether you’re a research institution, a pharmaceutical company, or a supplement manufacturer, Maxmedchem offers tailored solutions for bulk orders of Urolithin A, including custom packaging, private labeling, and bulk supply options.
• Competitive Pricing: Despite the high quality of their UA , Maxmedchem offers competitive pricing, ensuring that customers get the best value for their investment.

Comparative Urolithin A vs Fisetin for Antioxidant for Health 

• Urolithin A is particularly valuable for improving mitochondrial health and muscle function, making it ideal for those seeking to maintain energy, physical health, and muscle strength as they age.
• Fisetin, on the other hand, is a powerful broad-spectrum antioxidant that targets oxidative stress, inflammation, and senescent cells, with significant benefits for brain health and overall anti-aging support.

Supplement Formulation and Availability

Supplements of both compounds are increasingly available with formulations designed to improve bioavailability and efficacy, especially in liposomal or micronized forms. The market offers Urolithin A in capsule, tablet, or powder forms, while Fisetin is found in a wide variety of formats, including combinations with other cognitive and anti-aging ingredients. Whether used separately or together, these compounds are valuable tools in a comprehensive approach to cellular health, longevity, and anti-aging.

What is the Recommended Dosage?

Urolithin A: Urolithin A is typically taken in doses ranging from as a common dose, particularly in research exploring its effects on mitochondrial health and aging.

Fisetin: The most common dosage ranges from 100 mg to 500 mg per day. In research studies, doses between 100 mg and 500 mg per day have been used, often for 1-3 months, depending on the goal.

As a Urolithin A supplier, you can help ensure that you’re getting the benefits of these powerful antioxidants safely and effectively by sticking to the recommended dosages.

How it’s Absorbed and Excreted?

1.Urolithin A: Absorption and Excretion

Absorption:

Once Urolithin A is produced in the gut by the microbial conversion of ellagic acid, it can then be absorbed into the bloodstream through the lining of the intestines. The absorption process is fairly efficient, but it’s influenced by the diversity and composition of your gut microbiome. Not everyone’s gut bacteria are equally good at making Urolithin A from ellagic acid, so some people may not produce it as effectively as others. Once in the bloodstream, Urolithin A is transported to various tissues in the body, including muscles, liver, and brain.

Excretion:

The body doesn’t retain Urolithin A for long. It is primarily metabolized in the liver into other forms and then excreted through urine. As with many compounds processed in the liver, it goes through phases of conjugation (where it is combined with other molecules to make it easier to excrete). These conjugated forms are then filtered by the kidneys and expelled in the urine.

Urolithin A follows a relatively straightforward pathway: gut bacteria produce it, it’s absorbed into the bloodstream, does its job at the cellular level (especially in mitochondria), and is eventually eliminated in the urine.

2.Fisetin: Absorption and Excretion

Absorption:

Fisetin, unlike Urolithin A, is directly absorbed into your bloodstream when consumed, particularly when taken in supplement form. After ingestion, it passes through the stomach and is absorbed in the small intestine.

Excretion:

After Fisetin has been metabolized, it is excreted primarily through the urine as well. Once absorbed, Fisetin undergoes liver metabolism, where it is converted into various metabolites. These metabolites are then filtered out by the kidneys and eliminated via urine. Since Fisetin is not stored in the body for long periods, it is unlikely to accumulate in tissues, making it a safe compound to use on a consistent basis.

Advantages of Urolithin A Powder Bulk

If you’re considering Urolithin A bulk powder, there are several advantages that make it a smart choice. Here’s why you might want to think about adding it to your routine:

1. Cost-Effective

Buying bulk powder is often a more affordable way to get Urolithin A, especially if you plan to use it regularly. Instead of purchasing pre-formulated capsules or tablets, which can be more expensive due to packaging and branding, you can buy in bulk and save money in the long run.

2. Customizable Dosage

With bulk powder, you have complete control over how much you take. Whether you prefer smaller doses spread out throughout the day or a higher dose in a single serving, the flexibility to adjust the amount allows you to personalize your intake.

3. Purity and Potency

Bulk powders often have fewer additives and fillers compared to pre-capsulated or pre-formulated products. This means you get a pure form of UA.

Where Can You Buy Urolithin A and Fisetin from?

As a cosmetics supplier or supplyments manufacturer, sourcing high-quality Urolithin A is essential for maintaining the performance and integrity of your products. If you need COA, please Contact us!

FAQ

1. Is Urolithin A safe to use?

Urolithin A is generally considered safe when used at recommended doses. There have been no significant reports of toxicity or adverse reactions in the typical doses used for supplementation. As with any supplement, it’s important to use it as directed, and if you have any underlying health conditions or are pregnant or breastfeeding, consult a healthcare provider before using Urolithin A powder.

2. How long does it take to see results from Urolithin A powder?

The time it takes to see noticeable results from Urolithin A powder can vary depending on factors like your overall health, diet, and lifestyle. Some people may start to notice benefits such as increased energy or improved muscle recovery within a few weeks, while others may take longer. For anti-aging effects, consistent use over a period of 1–3 months may be necessary to see significant improvements in skin health and cellular rejuvenation.

3. Can I take Urolithin A powder with other supplements?

Yes, Urolithin A can generally be taken alongside other supplements, particularly those aimed at supporting overall health and wellness. It pairs well with other antioxidants, anti-aging compounds, or muscle recovery supplements. However, make sure there are no adverse interactions between urolixin A and other dietary supplements.