TRAMADOL HYDROCHLORIDE

Description

What is TRAMADOL HYDROCHLORIDE?

Tramadol hydrochloride is utilized to assuage moderate to modestly serious agony. Tramadol expanded discharge tablets and containers are just utilized by individuals who are supposed to require prescription to alleviate torment nonstop. Tramadol hydrochloride ingredients is in a class of prescriptions called sedative (opiate) analgesics. It works by having an impact on the manner in which the cerebrum and sensory system answer torment.

Tramadol hydrochloride high comes as a tablet, an answer (fluid), a drawn out discharge (long-acting) tablet, and a lengthy delivery (long-acting) container to take by mouth. The standard tablet and arrangement are taken normally regardless of food each 4 to 6 hours on a case by case basis. The lengthy delivery tablet and broadened discharge case ought to be required one time per day. Take the drawn out discharge tablet and the lengthy delivery container at about a similar season of day consistently.

Assuming that you are taking the drawn out discharge container, you might take it regardless of food. Assuming you are taking the drawn out discharge tablet, you ought to either consistently take it with food or consistently take it without food. Take tramadol hydrochloride ingredients precisely as coordinated. Try not to accept more prescription as a solitary portion or take a bigger number of dosages each day than recommended by your primary care physician. Taking more tramadol than endorsed by your PCP or in a manner that isn’t suggested may cause serious secondary effects or demise.

TRAMADOL HYDROCHLORIDE Basic Information

Product Name:	Tramadol hydrochloride
Synonyms:	AURORA KA-863; (+/-)-CIS-2-(DIMETHYLAMINOMETHYL)-1-(3-METHOXYPHENYL)CYCLOHEXANOL HYDROCHLORIDE; CIS-TRAMADOL HYDROCHLORIDE; O-DESMETHYL-CIS-TRAMADOL HCL; TRAMADOL HCL; TRAMODOL HCL; TRAMADOL HYDROCHLORIDE; 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-1-cyclohexanol hydrochloride
CAS:	22204-88-2
MF:	C16H26ClNO2
MW:	299.84
EINECS:	220-831-4
Product Categories:	Opioid receptor and opioid-like receptor; Intermediates & Fine Chemicals; Pharmaceuticals
Mol File:	22204-88-2.mol

Tramadol Hcl Chemical Structure

Tramadol hydrochloride

Tramadol Hydrochloride Tablets Chemical Properties

Melting point	171°C
Fp	9℃
storage temp.	2-8°C
CAS DataBase Reference	22204-88-2(CAS DataBase Reference)

TRAMADOL HYDROCHLORIDE Usage And Synthesis

Chemical Properties	White Cyrstalline Solid
Uses	An Analgesic
Manufacturing Process	5 g of magnesium turnings are treated while stirring with a mixture of 37.4 g of m-bromoanisole and 160 ml of absolute tetrahydrofuran at such a rate that the reaction mixture boils gently because of the heat produced by the immediately starting reaction. Thereafter, the reaction mixture is boiled under reflux while stirring until all the magnesium dissolves. The reaction mixture is cooled to 0°C to -10°C and then a mixture of 23.25 g of 2- dimethylaminomethylcyclohexanone and 45 ml of absolute tetrahydrofuran is added dropwise. The resulting mixture is stirred for 4 hours at room temperature and then poured, while stirring slowly, into a mixture of 25 g of ammonium chloride, 50 ml of water and 50 g of ice. The layers are separated and the aqueous layer is extracted twice with 50 ml portions of ether. The organic layers are combined, dried with sodium sulfate and evaporated. The residue is distilled, and 1-(m_x0002_methoxyphenyl)-2-dimethylaminomethyl-cyclohexanol-(1), boiling point at 0.6 mm Hg 138°C to 140°C, is obtained in a yield of 78.6% of theoretical. The hydrochloride obtained from the product, e.g., by dissolving in ether and treating with dry hydrogen chloride, melts at 168°C to 175°C. By recrystallization from moist dioxan this hydrochloride is separated into isomers melting at 162°C to 163°C and 175°C to 177°C, respectively.
Therapeutic Function	Analgesic

Tramadol hydrochloride Preparation Products And Raw materials

Raw materials

Hydrochloric acid–>Tetrahydrofuran–>Acetone–>Ammonium chloride–>1,4-Dioxane–>Dimethylamine–>Iodine–>Paraformaldehyde–>Cyclohexane–>Cyclohexanone–>3-Bromoanisole–>2-Piperazinecarboxylic acid methyl ester–>2-[(dimethylamino)methyl]cyclohexan-1-one–>Magnesium

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological activity:

3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride[1][2].

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

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