Tobramycin Sulfate

Description

Tobramycin Sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and fixes the 30 S-50 S ribosomal complex at the start codon (AUG), interfering with the initiation of protein synthesis. In addition, this agent induces misreading of the mRNA template, which results in 1) detachment of the ribosomal complex and inhibition of protein elongation or 2) incorporation of the incorrect amino acids into the growing polypeptide chain and the production of abnormal or nonfunctional proteins. Altogether, cell permeability is altered and cell death ensues. (Source: NCI Thesaurus (NCIt))

Tobramycin sulfate Basic information

Product Name:	Tobramycin sulfate
Synonyms:	TOBRAMYCIN SULFATE SALT;TOBRAMYCIN SULPHATE;(2S,3R,4S,5S,6R)-4-amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxy-2-oxanyl]oxy]-2-hydroxycyclohexyl]oxy-6-(hydroxymethyl)oxane-3,5-diol;Dartobcin;Dicon;Nebcine;Tobra gobens;Tobramycin sulfate [usan]
CAS:	79645-27-5
MF:	C18H39N5O13S
MW:	565.59
EINECS:	616-717-2
Product Categories:	API; API’s; Aminoglycosides Antibiotics; Antibacterial; Antibiotics; Antibiotics by Application
Mol File:	79645-27-5.mol

TOBRAMYCIN SULFATE SALT Chemical Structure

Tobramycin sulfate

TOBRAMYCIN SULPHAT Chemical Properties

storage temp.	2-8°C
Water Solubility	Soluble in water (50 mg/ml).
CAS DataBase Reference	79645-27-5(CAS DataBase Reference)

TOBRAMYCIN SULPHAT Usage And Synthesis

Uses	Tobramycin Sulfate is an antibiofilm formulations.

Maxmedchem, a global supplier of Tobramycin sulfate, 79645-27-5 offers for your requirements of RND / Development quantities or commercials, based on status of the product. We can also offer its intermediates with supportive technical package required for evaluation.

Functions and features:

1. Antibacterial effect: Tobramycin Sulfate mainly kills or inhibits the growth of bacteria by inhibiting bacterial protein synthesis. It has a strong bactericidal effect against a range of Gram-negative bacteria, including those with high drug resistance.
2. Wide range of uses: Commonly used to treat respiratory infections, such as bacterial pneumonia, bronchitis, capsular fibrosis, etc. It can also be used to treat dacryocystitis, urinary tract infections, skin infections and other diseases.
3. Medical route: Tobramycin Sulfate can be administered by mouth, injection, or topical application, but it is usually more common to give it intravenously for severe infections, especially those that require rapid treatment. .

Precautions for use:

– Use strictly according to your doctor’s recommendations and drug package insert instructions, including dosage and frequency of use.
– If allergic reactions or adverse reactions (such as rash, difficulty breathing, etc.) occur, stop use immediately and consult a doctor.
– Long-term use may lead to drug resistance, so avoid misuse or inappropriate use of antibiotics.

Precautions:

– Pregnant women, lactating women, children and people with specific diseases or taking specific medications should use it under the guidance of a doctor.
– It is not recommended to change or stop using medications on your own unless under the guidance of a doctor.

MSDS: MSDS available

COA: COA can be available if you send us inquiry.

Email us at: info@maxmedchem.com for more details.