Tigecycline

Description

What is Tigecycline?

Tigecycline is tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms. It has a role as an antibacterial drug. It is a member of tetracyclines and a tertiary alpha-hydroxy ketone. It is a conjugate base of a tigecycline(1+).

Basic information

Product Name:	Tigecycline
Synonyms:	Tigecycline hydrate; Tigilcycline; Tigecyclin; Tigecycline 95%
CAS:	220620-09-7
MF:	C29H39N5O8
MW:	585.65
EINECS:	685-736-6
Product Categories:	pharmaceutical intermediate; Amines; API; Intermediates & Fine Chemicals; Pharmaceuticals; Tetracycline Drugs

Chemical Structure

Tigecycline

Chemical Properties

Melting point	164-166°C
Boiling point	890.9±65.0 °C(Predicted)
density	1.45±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka	4.50±1.00(Predicted)
form	Orange powder
Merck	14,9432

Tigecycline Uses And Synthesis

Tigecycline is a parenteral glycycline antibiotic used for treatment of serious infections due to susceptible organisms. Tigecycline therapy is sometimes accompanied by minor aminotransferase elevations, but has not been definitely associated with clinically apparent liver injury with jaundice.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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