Theophylline

Description

What is Theophylline?

Theophylline is an orally administered xanthine derivative that induces relaxation of smooth muscle in the bronchial tree causing bronchodilation. Theophylline is widely used in therapy of asthma and is not believed to cause liver injury.

It is tonic and skin conditioning. Its cosmetic activity is not clearly or definitively established. It is most often found in anti-cellulite products. Theophylline is in the same family of bio chemicals as caffeine. It is naturally occurring in tea.

Basic Information

Product Name:	Theophylline
Synonyms:	Elixophyllin; accurbron;Acet-theocin; aminophylline;
CAS:	58-55-9
MF:	C7H8N4O2
MW:	180.16
EINECS:	200-385-7
Product Categories:	pharmaceutical intermediate;Bulk Drug Intermediates;Asthma drugs;APIs;Respiratory Drugs

Chemical Structure

Chemical Properties

Melting point	271-273 °C
Boiling point	312.97°C (rough estimate)
density	1.3640 (rough estimate)
refractive index	1.6700 (estimate)
Fp	11 °C
storage temp.	2-8°C
solubility	0.1 M HCl: soluble
pka	8.77(at 25℃)
form	powder
color	white
Water Solubility	8.3 g/L (20 ºC)
BRN	13463
Stability:	Stable. Incompatible with strong oxidizing agents.

What is theophylline used for

Theophylline is structurally similar to caffeine and is found in green and black tea. It has a role as a vasodilator agent, a bronchodilator agent, a muscle relaxant, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor, an anti-asthmatic drug, an anti-inflammatory agent, an immunomodulator, an adenosine receptor antagonist, a drug metabolite, a fungal metabolite and a human blood serum metabolite.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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