Quercetin

Description

What is Quercetin?

Quercetin is a flavonoid found in many foods and herbs and is a regular component of a normal diet. Extracts of quercetin have been used to treat or prevent diverse conditions including cardiovascular disease, hypercholesterolemia, rheumatic diseases, infections and cancer but have not been shown to be effective in clinical trials for any medical condition. Quercetin as a nutritional supplement is well tolerated and has not been linked to serum enzyme elevations or to episodes of clinically apparent liver injury.(Source: LiverTox)

Quercetin Basic information

Product Name:	Quercetin
Synonyms:	meletin; sophoretin; xanthaurine; quercetine; quercetol; quertine; kvercetin; quercetin supplement
CAS:	117-39-5
MF:	C15H10O7
MW:	302.24
EINECS:	204-187-1
Product Categories:	Plant extracts; Pharmaceutical Raw Materials; pharmaceutical intermediate; Respiratory Drugs

Chemical Structure

Quercetin

Quercetin Chemical Properties

Melting point	316.5 °C
Boiling point	363.28°C (rough estimate)
density	1.3616 (rough estimate)
refractive index	1.4790 (estimate)
storage temp.	room temp
pka	6.31±0.40(Predicted)
form	solid
Water Solubility	<0.1 g/100 mL at 21 ºC
Merck	13,8122
BRN	317313
InChIKey	REFJWTPEDVJJIY-UHFFFAOYSA-N

Quercetin Usage And Synthesis

Quercetin Uses

1. It can be used as a kind of antioxidant which is mainly used for oil, drinks, cold drinks, meat processing products.
2. It has good effects of expectorant, anti-cough, anti-asthma and can be used for treating chronic bronchitis as well as for adjuvant therapy of coronary heart disease and high blood pressure.

3. It can also be used as analytical standards

Quercetin Pharmacological effects

Quercetin can significantly inhibit the effect of cancer-promoting agent, inhibiting the growth of malignant cells in vitro, inhibiting the DNA, RNA, and protein synthesis of Ehrlich ascites tumor cells.
Quercetin has effects of inhibiting the platelet aggregation and the release effect of serotonin (5-HT) as well as inhibiting the platelet aggregation process which is induced by ADP, thrombin and platelet-activating factor (PAF) in which having the strongest inhibition effect on PAF. Moreover, it can also inhibit thrombin-induced the release of platelet 3H-5-HT of rabbit.

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