Pyridoxine and its Medical use

Pyridoxine is a form of vitamin B6 that is commonly found in foods and used as a dietary supplement.As a supplement, it is used to treat and prevent pyridoxine deficiency, sideroblastic anemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of Mushroom poisoning.It is used orally or by injection.It is generally well tolerated.Occasional side effects include headache, numbness, and drowsiness.Normal doses are safe during pregnancy and breastfeeding.Pyridoxine belongs to the B vitamin group.The body needs it to metabolize amino acids, carbohydrates and lipids.Dietary sources include fruits, vegetables, and grains.

Medical use

As a therapy (oral or injectable), it is used to treat or prevent pyridoxine deficiency, sideroblastic anemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects of isoniazid therapy, and certain Some types of mushrooms are poisonous.Isoniazid is an antibiotic used to treat tuberculosis.Common side effects include numbness in the hands and feet.Co-treatment with vitamin B6 may reduce numbness.Pyridoxine-dependent epilepsy is a rare form of infantile epilepsy that does not improve with typical antiepileptic drugs.Pyridoxine in combination with doxylamine for the treatment of morning sickness in pregnant women.

Side effects

It is generally well tolerated, but overdose toxicity may occur.Occasional side effects include headache, numbness, and drowsiness.Pyridoxine overdose can cause peripheral sensory neuropathy, which is characterized by poor coordination, numbness, and decreased sensations of touch, temperature, and vibration.Pyridoxine concentrations in the blood of healthy individuals range from 2.1 to 21.7 ng/mL.Normal doses are safe during pregnancy and breastfeeding.

Mechanism

Pyridoxine belongs to the B vitamin group.The body needs it to make amino acids, carbohydrates, and lipids.Dietary sources include fruits, vegetables, and grains.It is also required for the activity of muscle phosphorylases associated with glycogen metabolism.