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Penicillin G Sodium Salt
- Chemical Name:Penicillin G sodium salt
- CAS No.:69-57-8
- MF:C16H17N2NaO4S
- MW:356.37
- Specification: USP|EP|BP
- Purity:>98% or As customer requested
- Color: colorless or white
- Solubility：5-10 g/100 mL at 25 ºC
- Product Categories: Pharmaceutical raw chemicals; API; antibiotic; Biochemistry
- Test method: HPLC
Description
Penicillin G Sodium Salt is the sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.
Inactivation of Penicillin G Sodium Salt interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Penicillin G sodium salt Basic information
| Product Name: | Penicillin G sodium salt |
| Synonyms: | benzyl penicillinic acid sodium salt; sodium penicillinii;BENZYL PENICILLIN SODIUM;BENZYLPENICILLIN SODIUM SALT |
| CAS: | 69-57-8 |
| MF: | C16H17N2NaO4S |
| MW: | 356.37 |
| EINECS: | 200-710-2 |
| Product Categories: | Pharmaceutical raw chemicals; API; antibiotic; Biochemistry |
Benzylpenicillin sodium Chemical Structure
Crystapen Chemical Properties
| Melting point | 209-212°C |
| alpha | D24.8 +301° (c = 2.0 in water) |
| density | 1.41 |
| refractive index | 300 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days. |
| form | powder |
| color | colorless or white |
| PH | 5.5-7.5 (3% in H2O) |
| Water Solubility | 5-10 g/100 mL at 25 ºC |
| Merck | 14,7094 |
| BRN | 3834217 |
| Stability: | Stability Stable, but incompatible with a wide variety of materials, including acids, oxidizing agents, heavy metals, alcohols, glycerol, thiomersal, many surface-active agents, alkalies, peroxides, reducing agents, lanolin, glycol, sugars, amines, iodine, iodides, thiols. Hygroscopic. |
Crystapen Usage And Synthesis
| Chemical Properties | White powder |
| Uses | Sodium salt of Penicillin G, an antibacterial, antimicrobial medication. Used in the treatment of pneumococcus and streptococcus bacterial infections. |
| World Health Organization (WHO) | Penicillin is listed separately in the WHO Model List of Essential Drugs. |
| General Description | White to slightly yellow crystalline powder with a faint odor. pH (10% solution) 5.5-7.5. |
| Air & Water Reactions | Water soluble. |
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