Pharmacology of Cetirizine
PharmacodynamicsCetirizine acts as a highly selective antagonist of histamine H1 receptors. [3] The Ki values for the H1 receptor are approximately 6 nM for cetirizine, approximately 3 nM for levocetirizine, and approximately 100 nM for dexetirizine, indicating that the levo-enantiomer is the predom