Netilmicin Sulfate
- Chemical Name:Netilmicin sulfate
- CAS No.:56391-57-2
- MF: C42H92N10O34S5
- MW: 1441.55
- Specification: USP|EP|BP
- Purity: >98% or As customer requested
- Appearance: white to faint yellow
- Solubility:H2O: soluble10mg/mL
- Product Categories: Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals
- Test method: HPLC
Description
Netilmicin Sulfate is the sulfate salt form of netilimicin, a semisynthetic, water soluble aminoglycoside antibiotic. Netilmicin is derived from sisomicin, a naturally occurring aminoglycoside antibiotic produced by the fermentation of Micromonospora inyoensis. Netilmicin irreversibly binds to the 16S rRNA and S12 protein of the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, netilmicin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death. (Source: NCI Thesaurus (NCIt))
Product Name: | Netilmicin sulfate |
Synonyms: | D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-N1-ethyl-, sulfate (2:5);Netilmicin sulfhate;Netilmicin sulfate(2:5);Netilmicin sulphate, 1-N-Ethylsisomicin;6-diamino-2,3,4,6-tetradeoxy-alpha-d-glycero-hex-4-enopyranosyl-(1-4)-6)-o-(;netromycin;sulfate(2:5)(salt);Sulfate NetilMicin |
CAS: | 56391-57-2 |
MF: | C42H92N10O34S5 |
MW: | 1441.55 |
EINECS: | 260-147-3 |
Product Categories: | Active Pharmaceutical Ingredients; Intermediates & Fine Chemicals; Pharmaceuticals |
Mol File: | 56391-57-2.mol |
Netilmicin sulfate Chemical Structure
Melting point | >194°C (dec.) |
Boiling point | 868℃ |
storage temp. | 2-8°C |
solubility | H2O: soluble10mg/mL |
color | white to faint yellow |
Water Solubility | Soluble in water |
Sensitive | Light Sensitive & Hygroscopic |
EPA Substance Registry System | Netilmicin sulfate (56391-57-2) |
Nettacin Usage And Synthesis
Chemical Properties | Off-White to Pale Beige Solid |
Uses | antibiotics |
Uses | Semisynthetic aminoglycoside antibiotic, related to sisomicin. Antibacterial. |
MSDS: MSDS available
COA: COA can be available if you send us inquiry.
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