Levofloxacin HeMihydrate

Description

What is Levofloxacin?

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth. Levofloxacin is also a Quinolone Antimicrobial.

Basic information

Product Name:	Levofloxacin heMihydrate
Synonyms:	LEVOFLOXACIN HYDROCHLORIDE; LEVOFLOXACIN HCL; Levofloxacin hydrate
CAS:	138199-71-0
MF:	C18H22FN3O5
MW:	379.39
EINECS:	604-067-2
Product Categories:	Pharmaceutical raw materials;APIs;Intermediates & Fine Chemicals;Synthetic Anti-infective Drugs; Quinolones

Chemical Structure

Levofloxacin heMihydrate

Chemical Properties

Melting point	214-216°C
storage temp.	Sealed in dry,2-8°C
form	neat

How does levofloxacin hemihydrate work?

Levofloxacin may be used in the treatment of Acute Bacterial Sinusitis and Acute Exacerbation of Chronic Bronchitis when these infections have been adequately diagnosed. Resistance to fluoroquinolones of E. coli – the most common pathogen involved in urinary tract infections – varies across the European Union.

Levofloxacin heMihydrate is an antibiotic used against gram-negative organisms.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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