Diclofenac Sodium

Description

What is Diclofenac Sodium?

Diclofenac Sodium is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity.

Anti inflammatory sodium diclofenac is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. Diclofenac sodium for sale leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. (Source: NCI Thesaurus (NCIt))

Basic introduction of Diclofenac sodium

Product Name:	Diclofenac sodium
Synonyms:	N-(2,6-Dichlorophenyl)-o-aminophenylacetic acid sodium salt; sodium(o-((2,6-dichlorophenyl)amino)phenyl)acetate; sodium(o-(2,6-dichloroanilino)phenyl)acetate; sodiumdiclofenac; tsudohmin; AKOS B020028; 2-(2,6-DICHLOROANILINO)PHENYLACETIC ACID SODIUM SALT; 2-[(2,6-DICHLOROPHENYL)AMINO]-BENZENEACETIC ACID MONOSODIUM SALT
CAS:	15307-79-6
MF:	C14H10Cl2NNaO2
MW:	318.13
EINECS:	239-346-4
Product Categories:	Other APIs; VOLATREN; Organics; Amines; Aromatics; Heterocycles; Active Pharmaceutical Ingredients; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids; API’s; Lipid signaling
Mol File:	15307-79-6.mol

Sodiumdiclofenac Chemical Properties

Melting point	288-290°C
density	0.781 g/cm3
storage temp.	-20°C Freezer
solubility	H₂O: 50 mg/mL
pka	4(at 25℃)
form	White solid
Water Solubility	Soluble in water to 50mg/ml.
Merck	14,3081
Stability:	Stable.

Tsudohmin Safety Information

Hazard Codes	T,Xi
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	AG6330000
HazardClass	6.1(b)
PackingGroup	III
HS Code	29224999
Toxicity	LD50 in mice, rats (mg/kg): ~390, 150 orally (Krupp)

Diclofenac Sodium Benefits

Diclofenac Sodium is utilized to ease torment, enlarging (irritation), and joint solidness brought about by joint pain. Decreasing these side effects assists you with accomplishing a greater amount of your typical everyday exercises. This prescription is known as a nonsteroidal calming drug (NSAID).If you are treating an ongoing condition like joint inflammation, get some information about non-drug medicines as well as utilizing different meds to treat your aggravation. See additionally Warning area.

Anti inflammatory sodium diclofenac works by hindering the impact of synthetic compounds in your body, called cyclo-oxygenase (COX) chemicals. These catalysts help to make different synthetic compounds in the body, called prostaglandins. Prostaglandins are created at destinations of injury or harm, and cause torment and irritation. By hindering the impact of COX chemicals, less prostaglandins are created, and that implies torment and aggravation are facilitated.

There are two types of Diclofenac Sodium – diclofenac sodium and diclofenac potassium. The principal distinction between the two is that diclofenac potassium is assimilated into the body more rapidly than diclofenac sodium. A speedy activity is valuable where quick help with discomfort is required, and a delayed activity is more helpful in diminishing irritation.

A few brands of diclofenac likewise contain a medication called misoprostol. The brands are called Arthrotec® and Misofen®, and are endorsed for joint pain. Misoprostol assists with safeguarding the stomach against bothering which can be brought about by taking anti inflammatory sodium diclofenac throughout some stretch of time.

Diclofenac Sodium is definitely not a reasonable medication for individuals who have coronary illness (like cardiovascular breakdown), or who have circulatory issues, or who have had a respiratory failure or a stroke. This is on the grounds that it has been observed that there is a little expanded hazard of respiratory failure and stroke in this gathering. Other mitigating prescriptions are more reasonable for individuals with these circumstances – ask your primary care physician or drug specialist for counsel about an elective medication.

Diclofenac Sodium is likewise figured out as skin gels and fixes and as eye drops. There is more data about these definitions in the different medication pamphlets called Diclofenac gel/fix for torment and irritation, Diclofenac gel for sun harm, and diclofenac sodium for sale eye drops.