Cemandil Sodium Salt

Description

Cemandil Sodium Salt, also called as Cefamandole Nafate, is the sodium salt form of cefamandole formyl ester. Cemandil Sodium Salt is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, a semi-synthetic beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. (Source: NCI Thesaurus (NCIt))

Basic information

Product Name:	Cemandil sodium salt
Synonyms:	Cemandil sodium salt; CEFAMANDOLE NAFATE; Cefamandole Nafate (250 mg); Cefamandole Nafate (200 mg)
CAS:	42540-40-9
MF:	C19H17N6NaO6S2
MW:	512.49
EINECS:	255-877-4
Product Categories:	Intermediates & Fine Chemicals; Pharmaceuticals

Chemical Structure

Cemandil sodium salt

Chemical Properties

Melting point	190-193°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Freely soluble in water, sparingly soluble in methanol.
pka	2.6-3.0(at 25℃)
form	neat
Water Solubility	Freely soluble in water. Sparingly soluble in methanol

Usage And Synthesis

Chemical Properties: White Solid

Uses: Cephalosporin antibacterial.

Therapeutic Function: Antibiotic

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

Email us at: info@maxmedchem.com for more details.