Cefprozil Hydrate

Description

Cefprozil Hydrate Introduction

Cefprozil, (E)- is an E-isomer of a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil’s effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation. (Source: NCI Thesaurus (NCIt))

Cefprozil Basic information

Product Name:	Cefprozil hydrate
Synonyms:	7-[[2-amino-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-8-oxo-3-prop-1-enyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate; ceftibutin ;Cefprozil hydrate (Cefzil); Cefprozil for Suspension; (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propen-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, hydrate (1:1); (6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)acetamido]-8-oxo-3-propenyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate;Cefprozil (200 mg);CEFZIL
CAS:	121123-17-9
MF:	C18H21N3O6S
MW:	407.44
Product Categories:	DBI; Pharmaceutical intermediate
Mol File:	121123-17-9.mol

Cefprozil Chemical Structure

Cefprozil hydrate

Cefprozil Hydrate Chemical Properties

storage temp.	Store at 0-5°C
solubility	Slightly soluble in water and in methanol, practically insoluble in acetone.
CAS DataBase Reference	121123-17-9(CAS DataBase Reference)