Cefoselis Sulfate

Description

Cefoselis sulfate is broad-spectrum, oxime-type 4th generation cephalosporin antibiotic active against gram-positive and gram-negative aerobic bacteria. It occasionally induces seizures and convulsion in elder and renal failure patients by virtue of inhibiting GABA(A)-R in a competitive manner. Cefoselis sulfate inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs). This inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.

Basic information

Product Name:	Cefoselis sulfate
Synonyms:	CEFOSELIS SULFATE; Cefoselis sulfate USP/EP/BP
CAS:	122841-12-7
MF:	C19H24N8O10S3
MW:	620.64
EINECS:	1533716-785-6
Product Categories:	Inhibitors; pharmaceuticals; APIs

Chemical Structure

Cefoselis sulfate

Usage And Synthesis

Description	Cefoselis is a new fourth-generation cephalosporin and it is a parenteral antibiotic for a variety of infections including Staphylococcus aureus and Pseudornonas aeruginosa. Cefolesis is well tolerated in clinical studies, being eliminated mainly via glomerular filtration in humans.
Originator	Fujisawa (Japan)
Uses	antibiotic

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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