Apigenin

Description

What is Apigenin?

Apigenin, is widely distributed in tropical vegetables and fruits, especially celery is high in content; it is also high in some medicinal plants such as plantain, Trachelospermi Caulis, etc. The content of plant-derived beverages such as tea, wine and some condiments are also distributed. Apigenin belongs to flavonoids, and it is abundant in leaves of Apium graveolensvar. dulce, whole plants of Selaginella tamariscina and leaves of Sabinachinenesis. Apigenin exists in a variety of plants in the form of phyto yellow pigment. The pure product is a yellow powder, odorless and tasteless, and is a natural antioxidant.

Basic information

Product Name:	Apigenin
Synonyms:	4,5,7-Trihydroxyflavone; APIGENIN CRYSTALLINE; PARSLEY APIGENIN; Matricaria chamomilla flower; Versuline; Chamomile; Celery Extract; Versulin; Apigenol; Apigenine; synthetic Apigenin
CAS:	520-36-5
MF:	C15H10O5
MW:	270.24
EINECS:	208-292-3
Product Categories:	cosmetic; natural product; chemical reagent; pharmaceutical intermediate; Plant extract

Chemical Structure

Apigenin

Apigenin Chemical Properties

Melting point	>300 °C (lit.)
Boiling point	333.35°C (rough estimate)
density	1.2319 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	2-8°C
solubility	DMSO: 27 mg/mL
form	powder
pka	6.53±0.40(Predicted)
color	yellow
Merck	14,730
BRN	262620
InChIKey	KZNIFHPLKGYRTM-UHFFFAOYSA-N

Apigenin Uses

Natural Apigenin:

a. After sieving and crushing the celery seeds, place them in an alcohol container with a content of 70%. stirring and ensuring the liquid is stable.

b. Powdered celery seeds will become granular after fusion with alcohol;

c. The granular mixture in the container is extracted three times, and the time interval for each extraction is two hours;

d. The extracted particles are filtered through the solution, and after decompression and concentration treatments, the refined apigenin is made into powder.

Apigenin

Synthetic Apigenin:

The semi-synthetic method of apigenin is characterized by using naringenin as a raw material in an alkaline environment, reacting with iodine at a temperature of 50-130°C in 1,4-dioxane as a solvent, and oxidative dehydrogenation to Generate undefined apigenin, then after some special procudures, the undefined apigenin will become pure apigenin.

For apigenin uses:

A high number of studies carried out over the years have indicated that apigenin has many interesting pharmacological activities and nutraceutical potential. As an example, its properties as an antioxidant are well known, and it can also be a therapeutic agent to overcome diseases like inflammation, autoimmune, neurodegenerative disease, and even several types of cancers. It has a low intrinsic toxicity on normal versus cancerous cells, compared with other structurally related flavonoids.

Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

MSDS: MSDS available.

COA: COA can be available if you send us inquiry.

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