Amino acids are organic compounds containing basic amino groups and acidic carboxyl groups. The chemical formula is RCHNH2COOH. A compound formed by replacing the hydrogen atom on the carbon atom of a carboxylic acid with an amino group. Besides, they are the basic substances that constitute protein required for animal nutrition.
There are 22 kinds of Amino acids and the following is Amino acids chart:
Name |
Abbr |
Molecular |
Molecular |
Residue |
Residue Weight |
pKa1 |
pKb2 |
pKx3 |
pl4 |
Weight |
Formula |
Formula |
(-H2O) |
||||||
Alanine |
Ala |
89.1 |
C3H7NO2 |
C3H5NO |
71.08 |
2.34 |
9.69 |
– |
6 |
Arginine |
Arg |
174.2 |
C6H14N4O2 |
C6H12N4O |
156.19 |
2.17 |
9.04 |
12.48 |
10.76 |
Asparagine |
Asn |
132.12 |
C4H8N2O3 |
C4H6N2O2 |
114.11 |
2.02 |
8.8 |
– |
5.41 |
Aspartic acid |
Asp |
133.11 |
C4H7NO4 |
C4H5NO3 |
115.09 |
1.88 |
9.6 |
3.65 |
2.77 |
Cysteine |
Cys |
121.16 |
C3H7NO2S |
C3H5NOS |
103.15 |
1.96 |
10.28 |
8.18 |
5.07 |
Glutamic acid |
Glu |
147.13 |
C5H9NO4 |
C5H7NO3 |
129.12 |
2.19 |
9.67 |
4.25 |
3.22 |
Glutamine |
Gln |
146.15 |
C5H10N2O3 |
C5H8N2O2 |
128.13 |
2.17 |
9.13 |
– |
5.65 |
Glycine |
Gly |
75.07 |
C2H5NO2 |
C2H3NO |
57.05 |
2.34 |
9.6 |
– |
5.97 |
Histidine |
His |
155.16 |
C6H9N3O2 |
C6H7N3O |
137.14 |
1.82 |
9.17 |
6 |
7.59 |
Hydroxyproline |
Hyp |
131.13 |
C5H9NO3 |
C5H7NO2 |
113.11 |
1.82 |
9.65 |
– |
– |
Isoleucine |
Ile |
131.18 |
C6H13NO2 |
C6H11NO |
113.16 |
2.36 |
9.6 |
– |
6.02 |
Leucine |
Leu |
131.18 |
C6H13NO2 |
C6H11NO |
113.16 |
2.36 |
9.6 |
– |
5.98 |
Lysine |
Lys |
146.19 |
C6H14N2O2 |
C6H12N2O |
128.18 |
2.18 |
8.95 |
10.53 |
9.74 |
Methionine |
Met |
149.21 |
C5H11NO2S |
C5H9NOS |
131.2 |
2.28 |
9.21 |
– |
5.74 |
Phenylalanine |
Phe |
165.19 |
C9H11NO2 |
C9H9NO |
147.18 |
1.83 |
9.13 |
– |
5.48 |
Proline |
Pro |
115.13 |
C5H9NO2 |
C5H7NO |
97.12 |
1.99 |
10.6 |
– |
6.3 |
Pyroglutamatic |
Glp |
139.11 |
C5H7NO3 |
C5H5NO2 |
121.09 |
– |
– |
– |
5.68 |
Serine |
Ser |
105.09 |
C3H7NO3 |
C3H5NO2 |
87.08 |
2.21 |
9.15 |
– |
5.68 |
Threonine |
Thr |
119.12 |
C4H9NO3 |
C4H7NO2 |
101.11 |
2.09 |
9.1 |
– |
5.6 |
Tryptophan |
Trp |
204.23 |
C11H12N2O2 |
C11H10N2O |
186.22 |
2.83 |
9.39 |
– |
5.89 |
Tyrosine |
Tyr |
181.19 |
C9H11NO3 |
C9H9NO2 |
163.18 |
2.2 |
9.11 |
10.07 |
5.66 |
Valine |
Val |
117.15 |
C5H11NO2 |
C5H9NO |
99.13 |
2.32 |
9.62 |
– |
5.96 |
Notes:
1 pKa is the negative of the logarithm of the dissociation constant for the -COOH group.
2 pKb is the negative of the logarithm of the dissociation constant for the -NH3 group.
3 pKx is the negative of the logarithm of the dissociation constant for any other group in the molecule.
4 pl is the pH at the isoelectric point.
Reference: D.R. Lide, Handbook of Chemistry and Physics, 72nd Edition, CRC Press, Boca Raton, FL, 1991.
Lysine, tryptophan and other essential amino acid:
It means that the human body (or other vertebrates) cannot be synthesized or the synthesis speed is far from adapting to the needs of the body. It must be supplied by food protein. These amino acids are called essential amino acids. The requirement of essential amino acids for adults is about 20%~37% of the requirement of protein. There are 8 types of functions:
Lysine: promotes brain development, is a component of liver and gallbladder, can promote fat metabolism, regulate pineal gland, breast, corpus luteum and ovary, and prevent cell degradation;
Tryptophan: promote the production of gastric juice and pancreatic juice;
Phenylalanine: participates in eliminating the loss of kidney and bladder function;
Methionine (methionine): participates in the composition of hemoglobin, tissue and serum, and has the function of promoting the spleen, pancreas and lymph;
Threonine: has the function of transforming certain amino acids to achieve balance;
Isoleucine: Participates in the regulation and metabolism of the thymus, spleen and sub-brain glands; the sub-brain glands belong to the headquarters and act on the thyroid and gonads;
Leucine: balance isoleucine;
Valine: acts on the corpus luteum, breast and ovaries.
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