ERGOTAMINE TARTRATE

Description

What is ERGOTAMINE TARTRATE?

Ergotamine Tartrate is the tartrate salt type of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor movement.

Ergotamine tartrate specifically ties to alpha-adrenergic receptors along these lines animating vascular smooth muscle and causing vasoconstriction in the two supply routes and veins.

Ergotamine tartrate additionally obstructs serotonin 5-HT1D receptors, in this manner likewise causing vasoconstriction in cerebral veins. Narrowing of cerebral veins brought about by this specialist might lessen the blood stream and tension in cerebral supply routes and may free the agony from vascular migraines.

ERGOTAMINE TARTRATE Basic information

Product Name:	ERGOTAMINE TARTRATE
Synonyms:	(5α)-12′-Hydroxy-2′-Methyl-5′-(phenylMethyl)-ergotaMan-3′,6′,18-trione (2R,3R)-2,3-Dihydroxybutanedioate;ergotaMine tertrate dihydrate; L-Ascorbic acid,L-Threoascorbic acid, Antiscorbutic factor, VitaminC; ERGOTAMINE TARTRATE (ERGOT ALKALOIDW/BRO AD RANGE OF PHYS; ERGOTAMIN D-TARTRAT 97%; Ergotamine Tartrate (150 mg) (List Chemical); -,[theta-(theta,theta)]-2,3-dihydroxybutanedioate(2:1)(salt); 6’,18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-ergotaman-3(5’alpha)
CAS:	379-79-3
MF:	C70H76N10O16
MW:	1313.41
EINECS:	206-835-9
Product Categories:	Aromatics; Chiral Reagents; Heterocycles; Intermediates & Fine Chemicals; Pharmaceuticals; API; DEMADEX
Mol File:	379-79-3.mol

Gynergen Chemical Structure

ERGOTAMINE TARTRATE

Llingraine Chemical Properties

Melting point	~195 °C (dec.)(lit.)
alpha	D25 -125 to -155° (c = 0.4 in chloroform)
storage temp.	2-8°C
Merck	13,3696
BRN	6173437
CAS DataBase Reference	379-79-3(CAS DataBase Reference)
EPA Substance Registry System	Ergotamine tartrate (379-79-3)

ERGOTAMIN D TARTRAT 97% Usage And Synthesis

Chemical Properties	White Solid
Chemical Properties	Ergotamine tartrate is a crystalline solid.
Uses	Antimigraine.
Uses	diuretic, inhibits Na/K/2Cl carrier system
Brand name	Ergomar (Harvest);Ergostat (Parke-Davis); Wigrettes (Organon).
General Description	Powder or liquid forms available as drugs. Used in obstetrics and in the treatment of migraine headaches.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	ERGOTAMINE TARTRATE is sensitive to prolonged exposure to heat and light. . When heated to decomposition, ERGOTAMINE TARTRATE emits toxic fumes of nitrogen oxides. Protect from light and heat [EPA, 1998].