DL-Lysine Acetylsalicylate

Description

DL-Lysine acetylsalicylate, also called as aspirin DL-Lysine, which is the lysine salt form of acetylsalicylic acid, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activities. Like other NSAIDs, aspirin DL-lysine inhibits the activity of cyclooxygenase I and II, resulting in decreased formation of prostaglandins (PGs) and thromboxanes precursors. This leads to decreased PG synthesis by PG synthase. This agent also causes a decrease in the formation of thromboxane A2 synthesis by thromboxane synthase, thereby inhibiting platelet aggregation.

Basic Information

Product Name:	DL-Lysine acetylsalicylate
Synonyms:	LYSINE ACETYLSALICYLIC ACID; LYSINE ACETYLSALICYLATE; DL-LYSINE ACETYLSALICYLATE; aspirin dl-lysine; 2-(Acetyloxy)benzoate; Aspirin-D L-Lysine for Injection; Lysine, 2-(acetyloxy)benzoate (1:1); Lysine, monosalicylate acetate (ester), D
CAS:	62952-06-1
MF:	C15H22N2O6
MW:	326.34
EINECS:	263-769-3
Product Categories:	Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals
Mol File:	62952-06-1.mol

Chemical Structure

DL-Lysine acetylsalicylate

Chemical Properties

Melting point	154-156°C
Boiling point	464.39°C (rough estimate)
density	1.1829 (rough estimate)
refractive index	1.6280 (estimate)
storage temp.	-20°C Freezer
CAS DataBase Reference	62952-06-1(CAS DataBase Reference)
EPA Substance Registry System	Aspirin DL-lysine (62952-06-1)

Usage And Synthesis

Chemical Properties	Crystalline Solid
Uses	Non-steroidal anti-inflammatory drugs (NSAIDs) may inhibit cancer growth. Water soluble, injectable aspirin derivative. Analgesic; antipyretic; anti-inflammatory.
Safety Profile	Moderately toxic by ingestion andother routes. When heated to decomposition it emits toxicfumes of NOx.