Azlocillin Sodium

  • Chemical Name:Azlocillin sodium
  • CAS No.: 37091-65-9
  • MF: C20H22N5NaO6S
  • MW: 483.47
  • Specification: USP|EP|BP
  • Purity:>98% or As customer requested
  • Solubility:H2O: soluble50mg/mL
  • Product Categories: Active Pharmaceutical Ingredients; Miscellaneous
  • Test Method: HPLC

Description

Azlocillin Sodium is the sodium salt form of azlocillin, a semisynthetic, extended spectrum acylampicillin with antibacterial activity. 

Azlocillin Sodium binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, thereby inhibiting the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This prevents proper bacterial cell wall synthesis, thereby results in the weakening of the bacterial cell wall and eventually leading to cell lysis. 

Azlocillin sodium Basic information  

Product Name: Azlocillin sodium
Synonyms: sodium azlocillin; Azlocillin sodium salt; Securopen
CAS: 37091-65-9
MF: C20H22N5NaO6S
MW: 483.47
EINECS: 253-347-7
Product Categories: Active Pharmaceutical Ingredients; Miscellaneous

Azlocillin sodium Chemical Structure

Azlocillin sodium            

Azlocillin sodium salt Chemical Properties   

Fp  >110°(230°F)
storage temp.  room temp
solubility  H2O: soluble50mg/mL
form  powder
Water Solubility  Freely soluble in water

Azlocillin sodium salt Usage And Synthesis

Originator Securopen,Bayer,W. Germany,1977
Uses

Antibacterial; Bacterial transpeptidase inhibitor
Azlocillin sodium is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques.
Therapeutic Function Antibacterial

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