Erythromycin Ethylsuccinate

Description

Erythromycin Ethylsuccinate is the ethylsuccinate salt form of erythromycin, a broad-spectrum, topical macrolide antibiotic with antibacterial activity. Erythromycin ethylsuccinate diffuses through the bacterial cell membrane and reversibly binds to the 50S subunit of the bacterial ribosome. This prevents bacterial protein synthesis. Erythromycin ethylsuccinate may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved. (Source: NCI Thesaurus (NCIt))

Erythromycin ethylsuccinate Basic information

Product Name:	Erythromycin ethylsuccinate
Synonyms:	ERYTHROMYCIN 2′-(ETHYL BUTANEDIOATE);ERYTHROMYCIN 2′-(ETHYL SUCCINATE); ERYTHROMYCIN ETHYLSUCCINATE; erythrocinethylsuccinate; erythromycin,mono(ethylsuccinate); erythromycin,mono(ethylsuccinate)(ester); Succinic acid, monoester with erythromycin; Erythromycin 2”-[3-(ethoxycarbonyl)propionate]
CAS:	1264-62-6
MF:	C43H75NO16
MW:	862.05
EINECS:	215-033-8
Product Categories:	Organics; Antibacterial; Macrolides; Mechanism of Action;
Mol File:	1264-62-6.mol

Eryped Chemical Structure

Erythromycin ethylsuccinate

Erythroped Chemical Properties

Melting point	219-224 C
Boiling point	778.19°C (rough estimate)
density	1.1417 (rough estimate)
refractive index	1.5280 (estimate)
Fp	>110°(230°F)
storage temp.	2-8°C
solubility	ethanol: soluble50mg/mL
form	solid
pka	13.09±0.70(Predicted)
color	white
Water Solubility	Freely soluble in organic solvents, practically insoluble in water
CAS DataBase Reference	1264-62-6